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Chlorogenic acidWhat is chlorogenic acid
Chlorogenic acid is a depsidic acid generated from caffeic acid and quinic acid, and is a phenylpropanoid produced by the shikimic acid pathway in plants during aerobic respiration. compound.
The chlorogenic acid in green coffee beans accounts for 6% to 12% of the total weight (dry weight), which is the most acid in coffee and the main component that affects the taste of fruit acid in coffee. Chlorogenic acid is a kind of polyphenols that widely exists in various plants in nature, but the content of chlorogenic acid in most plants is not high, and the most abundant chlorogenic acid exists in the skin of unroasted green coffee beans.
Chlorogenic acid is the main reason for the bitter taste of coffee, and the higher the content of chlorogenic acid, the more bitter the coffee will be. In the process of high-temperature roasting of coffee, chlorogenic acid will be destroyed in large quantities, which is also the reason why the coffee beans turn brown and produce the unique aroma of coffee.
The chlorogenic acid in green coffee beans accounts for 6% to 12% of the total weight (dry weight), which is the most acid in coffee and the main component that affects the taste of fruit acid in coffee. Chlorogenic acid is a kind of polyphenols that widely exists in various plants in nature, but the content of chlorogenic acid in most plants is not high, and the most abundant chlorogenic acid exists in the skin of unroasted green coffee beans.
Chlorogenic acid is the main reason for the bitter taste of coffee, and the higher the content of chlorogenic acid, the more bitter the coffee will be. In the process of high-temperature roasting of coffee, chlorogenic acid will be destroyed in large quantities, which is also the reason why the coffee beans turn brown and produce the unique aroma of coffee.
BakeCoffee bean roasting chart
DrinksFood intake of caffeine and chlorogenic acid
** Excessive intake of caffeine will affect health. According to the assessment of the European Commission of Food Science Experts, the daily intake of caffeine per person is best controlled below 300 mg, about 2-3 cups.
The optimal daily intake of chlorogenic acid is 300-600mg, and the total daily intake of caffeine should not exceed 300mg (documents of the Ministry of Health and Welfare, refer to EU standards). Research reports at home and abroad: Drinking coffee in moderation is beneficial to the prevention of obesity, hypertension, cardiovascular disease, diabetes, stroke, dementia, and gout. Nerf bean contains thousands of complex components. The most well-known and very important active compounds are chlorogenic acid, caffeine and quinic acid.。
EffectEfficacy of chlorogenic acid on the human body documented in literature
1Enhance antioxidant capacity in the body
- Chlorogenic acid has the antioxidant capacity of ORAC (Oxygen Redical Absorption Capacity)(Biosci Biotechnol Biochem.2012.76(2):395-9.)
- Chlorogenic acid scavenges free radicals in the body to achieve antioxidant effects(Molecules. 2016,21, 708-15.)
2Chlorogenic acid lowers blood pressure
- Chlorogenic acid in green coffee beans has the effect of lowering blood pressure in spontaneously hypertensive rats and humans. (Biosci Biotechnol Biochem.2012.76(2):395-9.)
- Experiments on hypertensive rats and humans indicated that the daily intake of chlorogenic acid in green coffee beans at a dose of about 140-720 mg can reduce blood pressure. (Am J Hyper tens.)2008 Jan;21(1):23-7..;Nutr Metab Cardiovasc Dis. 2008 mJul;18(6):408-14.
3Chlorogenic acid lowers blood sugar
- Chlorogenic acid was found in a glucose tolerance test to lower blood sugar before insulin was administered (Diabetes Care .2009. Jun; 32 (6):102-35.)
- Chlorogenic acid inhibits glucose-6-phosphatase to reduce the breakdown of hepatic glycogen to release glucose, thus achieving the effect of lowering blood sugar. (J. Med Chem. 1997.Jan 17;40(2):137-45.)
- Studies on Zucker rats with obesity, hyperlipidemia and insulin resistance (fa/fa) found that chlorogenic acid can improve the plasma and liver cholesterol and triglyceride concentrations in vivo. (J Nutr Biochem.2002 Dec:13 (12):717-726.)
- Chlorogenic acid lowers the blood glucose concentration after meals by regulating glucose metabolism. (Nutra foods. 2007. 6(3) 13-17.)
4Burn fat and lose weight
- Chlorogenic acid can inhibit the activity of fatty acid synthesis (3-hydroxy-3-methylglutaryl CoA reductase, acyl CoA:cholesterol acytransferase) to regulate fat metabolism and achieve weight loss. (Food Chem Toxicol 2010Mar;48(3):937-43)
- Chlorogenic acid increases the expression of PPAR-α (Peroxisome roliferator-activated Receptor-α) mRNA and protein to regulate fat metabolism. (Food and ChemicalToxicology. 2010. 48(3), 937 - 943.)
- Human trials have pointed out that chlorogenic acid can increase the glucose in food to be metabolized and utilized in the body to achieve the effect of weight loss. (Int Med Res. 2007 NovDec;35(6):900-8.)
- Chlorogenic acid achieves fat burning effect by regulating glucose metabolism in the human body. (Nutra foods. 2007. 6(3) 13- 17.)
5Antitumor effect of chlorogenic acid
- Chlorogenic acid inhibits the transcription of gene promoters in cancer cells to achieve anti-tumor effects. (Foodand Chemical Toxicology. 2010. 38(5) , 467 - 471.)
6Skin care
- Okakitaro from Japan said that chlorogenic acid can prevent melanin precipitation, prevent dark spots, and fight reactive oxygen species to maintain skin elasticity and luster.